参考文献/References:
[1] Ledley F D. Nonviral Gene Therapy: The promise of genes as pharmaceutical products[J]. Human Gene Therapy, 1995, 6(9):1129.
[2] Merdan T, Kopecek J, Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer[J]. Advanced Drug Delivery Reviews, 2002, 54(5):715-758.
[3] Kozielski K L , Tzeng S Y , Hurtado D M B A , et al. Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic sirna delivery to primary human brain cancer cells[J]. ACS Nano, 2014, 8(4):3232-3241.
[4] Zhou J, Patel T R, Sirianni R W, et al. Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma[J]. Proceedings of the National Academy of Sciences, 2013, 110(29):11751-11756.
[5] Ryuta S, Bringas J R, Mcknight T R, et al. Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging[J]. Cancer Research, 2004, 64(7):2572-2579..
[6] Ning J, Wakimoto H. Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapy[J]. Frontiers in Microbiology, 2014：5.
[7] Bhise N S, Gray R S, Sunshine J C, et al. The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D-organotypic cultures[J]. Biomaterials, 2010, 31(31):8088-8096.
[8] Breunig M, Hozsa C, Lungwitz U, et al. Mechanistic investigation of poly (ethylene imine)based siRNA delivery: Disulfide bonds boost intracellular release of the cargo[J]. Journal of Controlled Release, 2008, 130(1):57-63.
[9] Matsumoto S, Christie R J, Nishiyama N, et al. Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery[J]. Biomacromolecules, 2009, 10(1):119-127.
[10] Targeted quantum dot conjugates for siRNA delivery[J]. Bioconjugate Chemistry, 2007, 18(5):1391-1396.
[11] Smith T T, Stephan S B, Moffett H F, et al. In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers[J]. Nature Nanotechnology, 2017, 12(8):813.
[12] Green J J, Langer R, Anderson D G. A combinatorial polymer library approach yields insight into nonviral gene delivery[J]. Accounts of Chemical Research, 2008, 41(6):749-759.
[13] Mangraviti A , Tzeng S Y , Kozielski K L , et al. Polymeric nanoparticles for non-viral gene therapy extend brain tumor survival in vivo[J]. ACS Nano, 2015, 9(2).
[14] Bishop C J, Ketola T M, Tzeng S Y, et al. The effect and role of carbon atoms in poly (β-amino esters) for DNA binding and gene delivery[J]. Journal of the American Chemical Society, 2013, 135(18):6951-6957.
[15] Sunshine J C, Akanda M I, Li D, et al. Effects of base polymer hydrophobicity and endgroup modification on polymeric gene delivery[J]. Biomacromolecules, 2011, 12(10):3592-3600.
[16] Alfredo Quiones Hinojosa, Tzeng S Y, Martinez E E, et al. Non-viral gene delivery nanoparticles based on Poly (β-amino esters) for treatment of glioblastoma[J]. Biomaterials, 2011, 32(23):5402-5410.